madison-feshuk.r-universe.dev

[usepa] ctxR 1.1.3.9000

feshuk.madison@epa.gov (Madison Feshuk) — Fri, 09 Oct 2026 12:29:35 GMT

Access chemical, hazard, bioactivity, and exposure data from the Computational Toxicology and Exposure ('CTX') APIs . 'ctxR' was developed to streamline the process of accessing the information available through the 'CTX' APIs without requiring prior knowledge of how to use APIs. Most data is also available on the CompTox Chemical Dashboard ('CCD') and other resources found at the EPA Computational Toxicology and Exposure Online Resources .

[usepa] tcpl 3.3.0.9000

feshuk.madison@epa.gov (Madison Feshuk) — Thu, 16 Oct 2025 18:19:21 GMT

The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, 'invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but 'tcpl' can be used to support diverse chemical screening efforts.

[usepa] tcplfit2 0.1.9

feshuk.madison@epa.gov (Madison Feshuk) — Thu, 24 Jul 2025 13:02:16 GMT

The tcplfit2 R package performs basic concentration-response curve fitting. The original tcplFit() function in the tcpl R package performed basic concentration-response curvefitting to 3 models. With tcplfit2, the core tcpl concentration-response functionality has been expanded to process diverse high-throughput screen (HTS) data generated at the US Environmental Protection Agency, including targeted ToxCast, high-throughput transcriptomics (HTTr) and high-throughput phenotypic profiling (HTPP). tcplfit2 can be used independently to support analysis for diverse chemical screening efforts.